Novel Psychoactive Substances (NPS) Screen 2, Serum/Plasma

Method(s)

Gas Chromatography/Mass Spectrometry (GC/MS)

Suggested CPT Code(s)

80307

New York State Approval Status

Approved

Turnaround Time

4 days (If Positive: 11 days)

Test Includes


1	2C-B	4-Bromo-2,5-Dimethoxyphenethylamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
2	2C-B-FLY	8-bromo-2,3,6,7-benzo-dihydro-difuran-ethylamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
3	2C-C	4-Chloro-2,5-dimethoxyphenethylamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
4	2C-E	2,5-dimethoxy-4-ethylphenethylamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
5	2C-I	2,5-dimethoxy-4-iodophenethylamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
6	2C-P	2,5-dimethoxy-4-propylphenethylamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
7	2C-T-2	4-ethylthio-2,5-dimethoxyphenethylamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
8	2C-T-4	2-[4-(isopropylthio)-2,5-dimethoxyphenyl]ethanamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
9	2C-T-7	2,5-dimethoxy-4-n-propylthiophenethylamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
10	3,4-DMMC	3,4-dimethylmethcathinone	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
11	4-MEC	4-methyl-ethcathinone	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
12	4-MTA	4-Methylthioamphetamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	5	NPS
13	5-IAI	5-Iodo-2-aminoindane	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
14	5-MeO-DALT	N,N-diallyl-5-methoxytryptamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
15	5-MeO-DiPT	5-Methoxy-N,N-Diisopropyltryptamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	200	NPS
16	5-MeO-DMT	5-methoxy-dimethyltryptamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	Hallucinogen, NPS
17	5-MeO-MiPT	5-methoxy-N-methyl-N-isopropyltryptamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	25	NPS
18	Alpha PBP	alpha-Pyrrolidinobutiophenone	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	25	NPS
19	Alpha PPP	alpha-Pyrrolidinopropiophenone	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	80	NPS
20	alpha-PVT	alpha-pyrrolidinopentiothiophenone	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
21	APB	Aminopropyl benzofuran	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
22	APDB	Aminopropyl dihydrobenzofuran	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	5	NPS
23	BDB	Benzodioxolylbutanamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
24	Brephedrone	4-Bromomethcathinone	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	50	NPS
25	Cathinone	Khat	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
26	DBZP	1,4-Dibenzylpiperazine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
27	DET	N,N-diethyltryptamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
28	Dimethylone	bk-MDDMA	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	50	NPS
29	DMT	Component of Ayahuasca; N,N-Dimethyltryptamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
30	DOB	4-Bromo-2,5-dimethoxyamphetamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS, Stimulant
31	DOM	2,5-dimethoxy-4-methylamphetamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
32	Ethylamphetamine		Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	20	NPS
33	Ethylethcathinone		Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	5	NPS
34	Ethylphenidate		Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	15	NPS
35	Fluoroamphetamine		Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	25	NPS
36	Fluoromethamphetamine		Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	20	NPS
37	MAPB	Methylaminopropyl benzofuran	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
38	MBDB	Methylbenzodioxolylbutanamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	50	NPS
39	MBZP	1-(4-Methylbenzyl)piperazine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
40	MDAI	5,6-methylenedioxy-2-aminoindane	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
41	MDPBP	3,4-methylendioxy-alpha-pyrrolidinobutiophenone	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
42	MDPPP	3',4'-Methylenedioxy-alpha-pyrrolidinopropiophenone	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	25	NPS
43	MeOPP	para-methoxyphenylpiperazine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	20	NPS
44	MeOPPP	4'-methoxy- alpha-Pyrrolidinopropiophenone	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	25	NPS
45	Methcathinone		Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	20	NPS, Stimulant
46	Methedrone		Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
47	Methiopropamine		Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	5	NPS
48	Naphyrone		Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS, Stimulant
49	MPBP	4'-methyl- alpha-Pyrrolidinobutiophenone	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	80	NPS
50	PMA	para-methoxyamphetamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	20	NPS
51	PMMA	para-methoxy-N-methylamphetamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	5	NPS
52	Pyrovalerone		Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	5	NPS
53	Other Findings		Gas Chromatography/Mass Spectrometry (GC/MS)

Reflex Tests

Test Code	Test Name
52324SP	Pyrrolidinophenone Confirmation (Qualitative), Serum/Plasma
52388SP	Hallucinogens and Stimulants Confirmation 2 (Qualitative), Serum/Plasma
52389SP	Phenethylamines Confirmation 2 (Qualitative), Serum/Plasma
52390SP	Pyrrolidinophenone Confirmation, Serum/Plasma

Compliance Statement

This test was developed and its performance characteristics determined by NMS Labs. It has not been cleared or approved by the US Food and Drug Administration.

Sample Type

Serum or Plasma

Requested Volume

Minimum Volume

3.1 mL

Special Handling

Submit with Chain of Custody.
Serum: Collect sample in Red top tube
Plasma: Collect sample in Lavender top tube (EDTA) or Pink top tube.
Promptly centrifuge and separate Serum or Plasma into a plastic screw capped vial using approved guidelines.

Sample Container

Plastic container (Trace metal-free rinsed with deionized water), Plastic container (preservative-free)

Additional Collection Instructions

Transport Temperature

Frozen

Light Protection

Not Required

Rejection Criteria

Received Room Temperature. Received Refrigerated. Polymer gel separation tube (SST or PST).

Rejection criteria pertain to clinical sample submissions only.

Stability

Room Temperature: Not Stable
Refrigerated: Not Stable
Frozen (-20 °C): 2 day(s)


1	2C-B	4-Bromo-2,5-Dimethoxyphenethylamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
2	2C-B-FLY	8-bromo-2,3,6,7-benzo-dihydro-difuran-ethylamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
3	2C-C	4-Chloro-2,5-dimethoxyphenethylamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
4	2C-E	2,5-dimethoxy-4-ethylphenethylamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
5	2C-I	2,5-dimethoxy-4-iodophenethylamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
6	2C-P	2,5-dimethoxy-4-propylphenethylamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
7	2C-T-2	4-ethylthio-2,5-dimethoxyphenethylamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
8	2C-T-4	2-[4-(isopropylthio)-2,5-dimethoxyphenyl]ethanamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
9	2C-T-7	2,5-dimethoxy-4-n-propylthiophenethylamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
10	3,4-DMMC	3,4-dimethylmethcathinone	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
11	4-MEC	4-methyl-ethcathinone	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
12	4-MTA	4-Methylthioamphetamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	5	NPS
13	5-IAI	5-Iodo-2-aminoindane	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
14	5-MeO-DALT	N,N-diallyl-5-methoxytryptamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
15	5-MeO-DiPT	5-Methoxy-N,N-Diisopropyltryptamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	200	NPS
16	5-MeO-DMT	5-methoxy-dimethyltryptamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	Hallucinogen, NPS
17	5-MeO-MiPT	5-methoxy-N-methyl-N-isopropyltryptamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	25	NPS
18	Alpha PBP	alpha-Pyrrolidinobutiophenone	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	25	NPS
19	Alpha PPP	alpha-Pyrrolidinopropiophenone	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	80	NPS
20	alpha-PVT	alpha-pyrrolidinopentiothiophenone	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
21	APB	Aminopropyl benzofuran	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
22	APDB	Aminopropyl dihydrobenzofuran	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	5	NPS
23	BDB	Benzodioxolylbutanamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
24	Brephedrone	4-Bromomethcathinone	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	50	NPS
25	Cathinone	Khat	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
26	DBZP	1,4-Dibenzylpiperazine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
27	DET	N,N-diethyltryptamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
28	Dimethylone	bk-MDDMA	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	50	NPS
29	DMT	Component of Ayahuasca; N,N-Dimethyltryptamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
30	DOB	4-Bromo-2,5-dimethoxyamphetamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS, Stimulant
31	DOM	2,5-dimethoxy-4-methylamphetamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
32	Ethylamphetamine		Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	20	NPS
33	Ethylethcathinone		Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	5	NPS
34	Ethylphenidate		Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	15	NPS
35	Fluoroamphetamine		Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	25	NPS
36	Fluoromethamphetamine		Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	20	NPS
37	MAPB	Methylaminopropyl benzofuran	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
38	MBDB	Methylbenzodioxolylbutanamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	50	NPS
39	MBZP	1-(4-Methylbenzyl)piperazine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
40	MDAI	5,6-methylenedioxy-2-aminoindane	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
41	MDPBP	3,4-methylendioxy-alpha-pyrrolidinobutiophenone	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
42	MDPPP	3',4'-Methylenedioxy-alpha-pyrrolidinopropiophenone	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	25	NPS
43	MeOPP	para-methoxyphenylpiperazine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	20	NPS
44	MeOPPP	4'-methoxy- alpha-Pyrrolidinopropiophenone	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	25	NPS
45	Methcathinone		Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	20	NPS, Stimulant
46	Methedrone		Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS
47	Methiopropamine		Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	5	NPS
48	Naphyrone		Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	10	NPS, Stimulant
49	MPBP	4'-methyl- alpha-Pyrrolidinobutiophenone	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	80	NPS
50	PMA	para-methoxyamphetamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	20	NPS
51	PMMA	para-methoxy-N-methylamphetamine	Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	5	NPS
52	Pyrovalerone		Gas Chromatography/Mass Spectrometry (GC/MS)	ng/mL	5	NPS
53	Other Findings		Gas Chromatography/Mass Spectrometry (GC/MS)

Example Report (Negative)

Example Report (Positive)

Interface Map

8210SP Novel Psychoactive Substances (NPS) Screen 2, Serum/Plasma - Current Version
Analyte	Units	Analyte Mapping Code
2C-B	ng/mL	HALD-2CB
2C-B-FLY	ng/mL	HALD-2CBFLY
2C-C	ng/mL	HALD-2CC
2C-E	ng/mL	HALD-2CE
2C-I	ng/mL	HALD-2CI
2C-P	ng/mL	HALD-2CP
2C-T-2	ng/mL	HALD-2CT2
2C-T-4	ng/mL	HALD-2CT4
2C-T-7	ng/mL	HALD-2CT7
3,4-DMMC	ng/mL	HALD-34DMMC
4-MEC	ng/mL	HALD-4MEC
4-MTA	ng/mL	HALD-4MTA
5-IAI	ng/mL	HALD-5IAI
5-MeO-DALT	ng/mL	HALD-5DAL
5-MeO-DiPT	ng/mL	HALD-5MEOD
5-MeO-DMT	ng/mL	HALE-5DMT
5-MeO-MiPT	ng/mL	HALD-MMIPT
Alpha PBP	ng/mL	HALM-APBP
Alpha PPP	ng/mL	HALM-APPP
alpha-PVT	ng/mL	HALD-APVT
APB	ng/mL	HALD-56APB
APDB	ng/mL	HALD-5APDB
BDB	ng/mL	HALD-BDB
Brephedrone	ng/mL	HALD-BREPH
Cathinone	ng/mL	HALE-CATHI
DBZP	ng/mL	HALD-DBZP
DET	ng/mL	HALE-DET
Dimethylone	ng/mL	HALD-DIMETH
DMT	ng/mL	HALE-DMT
DOB	ng/mL	HALD-DOB
DOM	ng/mL	HALD-DOM
Ethylamphetamine	ng/mL	HALD-NAMPH
Ethylethcathinone	ng/mL	HALD-ETHY4
Ethylphenidate	ng/mL	HALD-EPHEN
Fluoroamphetamine	ng/mL	HALD-FORAM
Fluoromethamphetamine	ng/mL	HALD-FORMA
MAPB	ng/mL	HALD-MAPB
MBDB	ng/mL	HALD-MBDB
MBZP	ng/mL	HALD-MBZP
MDAI	ng/mL	HALD-MDAI
MDPBP	ng/mL	HALD-MDPBP
MDPPP	ng/mL	HALH-MDPPP
MeOPP	ng/mL	HALD-MEOPP
MeOPPP	ng/mL	HALH-MEOPP
Methcathinone	ng/mL	HALE-MCATH
Methedrone	ng/mL	HALE-METHD
Methiopropamine	ng/mL	HALD-MPROP
Naphyrone	ng/mL	HALH-NAPHY
MPBP	ng/mL	HALH-MPBP
PMA	ng/mL	HALE-PMA
PMMA	ng/mL	HALD-PMMA
Pyrovalerone	ng/mL	HALH-PYROV
Other Findings		OTHERFIND

LOINC^® Information

8210SP Novel Psychoactive Substances (NPS) Screen 2, Serum/Plasma - Current Version
Analyte	Units	Analyte Mapping Code
2C-B	ng/mL	HALD-2CB
2C-B-FLY	ng/mL	HALD-2CBFLY
2C-C	ng/mL	HALD-2CC
2C-E	ng/mL	HALD-2CE
2C-I	ng/mL	HALD-2CI
2C-P	ng/mL	HALD-2CP
2C-T-2	ng/mL	HALD-2CT2
2C-T-4	ng/mL	HALD-2CT4
2C-T-7	ng/mL	HALD-2CT7
3,4-DMMC	ng/mL	HALD-34DMMC
4-MEC	ng/mL	HALD-4MEC
4-MTA	ng/mL	HALD-4MTA
5-IAI	ng/mL	HALD-5IAI
5-MeO-DALT	ng/mL	HALD-5DAL
5-MeO-DiPT	ng/mL	HALD-5MEOD
5-MeO-DMT	ng/mL	HALE-5DMT
5-MeO-MiPT	ng/mL	HALD-MMIPT
Alpha PBP	ng/mL	HALM-APBP
Alpha PPP	ng/mL	HALM-APPP
alpha-PVT	ng/mL	HALD-APVT
APB	ng/mL	HALD-56APB
APDB	ng/mL	HALD-5APDB
BDB	ng/mL	HALD-BDB
Brephedrone	ng/mL	HALD-BREPH
Cathinone	ng/mL	HALE-CATHI
DBZP	ng/mL	HALD-DBZP
DET	ng/mL	HALE-DET
Dimethylone	ng/mL	HALD-DIMETH
DMT	ng/mL	HALE-DMT
DOB	ng/mL	HALD-DOB
DOM	ng/mL	HALD-DOM
Ethylamphetamine	ng/mL	HALD-NAMPH
Ethylethcathinone	ng/mL	HALD-ETHY4
Ethylphenidate	ng/mL	HALD-EPHEN
Fluoroamphetamine	ng/mL	HALD-FORAM
Fluoromethamphetamine	ng/mL	HALD-FORMA
MAPB	ng/mL	HALD-MAPB
MBDB	ng/mL	HALD-MBDB
MBZP	ng/mL	HALD-MBZP
MDAI	ng/mL	HALD-MDAI
MDPBP	ng/mL	HALD-MDPBP
MDPPP	ng/mL	HALH-MDPPP
MeOPP	ng/mL	HALD-MEOPP
MeOPPP	ng/mL	HALH-MEOPP
Methcathinone	ng/mL	HALE-MCATH
Methedrone	ng/mL	HALE-METHD
Methiopropamine	ng/mL	HALD-MPROP
Naphyrone	ng/mL	HALH-NAPHY
MPBP	ng/mL	HALH-MPBP
PMA	ng/mL	HALE-PMA
PMMA	ng/mL	HALD-PMMA
Pyrovalerone	ng/mL	HALH-PYROV
Other Findings		OTHERFIND

Some LOINC^® codes may not have been assigned or are not available.

This material contains content from LOINC (http://loinc.org). LOINC is copyright ^® 1995-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC^® is a registered United States trademark of Regenstrief Institute, Inc.

The CPT Codes provided in this document are based on AMA Guidelines and are for informational purposes only. NMS Labs Does not assume responsibility for billing errors due to Reliance on the CPT Codes listed in this document.

*The information contained in this document represents database configurations, as they will appear on the effective date listed above.