Basic Drug Screen, Umbilical Cord Tissue

Purpose

Detection of in utero exposure to drugs of abuse consistent with maternal use during the second and third trimesters of pregnancy; Newborn (neonatal) toxicology

Method(s)

High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)

Suggested CPT Code(s)

80307

New York State Approval Status

Approved

Turnaround Time

1 days (If Positive: 3 days)

Test Includes


1	6-Monoacetylmorphine - Free	6-MAM; Heroin Metabolite	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/g	0.2
2	Amphetamine	Benzphetamine Metabolite	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/g	5	Anorexigenic, Stimulant
3	Benzoylecgonine	Cocaine Degradation Product	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/g	0.5	Stimulant
4	Codeine - Free		High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/g	0.5	Narcotic Analgesic
5	Delta-9 Carboxy THC	Inactive Metabolite of Delta-9 THC	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/g	0.1	Cannabinoid
6	Hydrocodone - Free	Vicodin®; Zohydro®	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/g	0.5	Narcotic Analgesic
7	Hydromorphone - Free	Dilaudid®; Hydrocodone Metabolite	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/g	0.5	Narcotic Analgesic
8	MDA	3,4-Methylenedioxyamphetamine; Adam; MDMA Metabolite	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/g	5	Stimulant
9	MDEA	3,4-methylenedioxyethylamphetamine; Eve	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/g	5	Stimulant
10	MDMA	3,4-Methylenedioxymethamphetamine; Ecstasy	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/g	5	Stimulant
11	Methamphetamine	Benzphetamine Metabolite	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/g	5	Stimulant
12	Morphine - Free		High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/g	0.5	Narcotic Analgesic
13	Phencyclidine	Angel Dust; Sherm; PCP	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/g	1.0	Hallucinogen

Test Also Known As

Neonatal

Reflex Tests

Test Code	Test Name
52345UC	Amphetamines Confirmation (Qualitative), Umbilical Cord Tissue
52357UC	Phencyclidine Confirmation (Qualitative), Umbilical Cord Tissue
52362UC	Cannabinoids Confirmation (Qualitative), Umbilical Cord Tissue
52363UC	Cocaine Metabolite Confirmation (Qualitative), Umbilical Cord Tissue
52391UC	Opiates - Free (Unconjugated) Confirmation (Qualitative), Umbilical Cord Tissue

Compliance Statement

This test was developed and its performance characteristics determined by NMS Labs. It has not been cleared or approved by the US Food and Drug Administration.

Sample Type

Umbilical Cord

Requested Volume

10 g

Minimum Volume

10 g

Special Handling

Collect at least 6 inches of umbilical cord (approximately the length of an adult hand). Drain and discard any blood. Rinse the exterior of the cord segment with normal saline or sterile water. Pat the cord dry and place in container for transport. Store at refrigerated temperature.

Unacceptable Specimens: Cords soaking in blood or other fluid. Formalin fixed. Tissue that is obviously decomposed. Samples received without cold pack.

Sample Container

Plastic container (preservative-free)

Additional Collection Instructions

Transport Temperature

Refrigerated

Light Protection

Not Required

Rejection Criteria

None

Rejection criteria pertain to clinical sample submissions only.

Stability

Room Temperature: Undetermined
Refrigerated: 7 day(s)
Frozen (-20 °C): 14 day(s)


1	6-Monoacetylmorphine - Free	6-MAM; Heroin Metabolite	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/g	0.2
2	Amphetamine	Benzphetamine Metabolite	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/g	5	Anorexigenic, Stimulant
3	Benzoylecgonine	Cocaine Degradation Product	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/g	0.5	Stimulant
4	Codeine - Free		High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/g	0.5	Narcotic Analgesic
5	Delta-9 Carboxy THC	Inactive Metabolite of Delta-9 THC	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/g	0.1	Cannabinoid
6	Hydrocodone - Free	Vicodin®; Zohydro®	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/g	0.5	Narcotic Analgesic
7	Hydromorphone - Free	Dilaudid®; Hydrocodone Metabolite	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/g	0.5	Narcotic Analgesic
8	MDA	3,4-Methylenedioxyamphetamine; Adam; MDMA Metabolite	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/g	5	Stimulant
9	MDEA	3,4-methylenedioxyethylamphetamine; Eve	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/g	5	Stimulant
10	MDMA	3,4-Methylenedioxymethamphetamine; Ecstasy	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/g	5	Stimulant
11	Methamphetamine	Benzphetamine Metabolite	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/g	5	Stimulant
12	Morphine - Free		High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/g	0.5	Narcotic Analgesic
13	Phencyclidine	Angel Dust; Sherm; PCP	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/g	1.0	Hallucinogen

Example Report (Negative)

Example Report (Positive)

Interface Map

9351UC Basic Drug Screen, Umbilical Cord Tissue - Current Version
Analyte	Units	Analyte Mapping Code	LOINC®
6-Monoacetylmorphine - Free	ng/g	TOF5-MAMF	97210-9
Amphetamine	ng/g	AMPS-AMPH	97220-8
Benzoylecgonine	ng/g	TOF3-ECGON	97222-4
Codeine - Free	ng/g	TOF5-CODEI	97236-4
Delta-9 Carboxy THC	ng/g	THC1-9CARB	97584-7
Hydrocodone - Free	ng/g	TOF5-HYDROC	97254-7
Hydromorphone - Free	ng/g	TOF5-HMF	97256-2
MDA	ng/g	AMPS-MDA1	97262-0
MDEA	ng/g	AMPS-MDEA	97264-6
MDMA	ng/g	AMPS-MDMA	97266-1
Methamphetamine	ng/g	AMPS-METHA	97274-5
Morphine - Free	ng/g	TOF5-MORPH	97280-2
Phencyclidine	ng/g	PHENCYCL	97298-4

52345UC Amphetamines Confirmation (Qualitative), Umbilical Cord Tissue- Current Version
Analyte	Units	Analyte Mapping Code
Amphetamine	ng/g	AMPS-AMPQL
MDA	ng/g	AMPS-MDAQL
MDEA	ng/g	AMPS-MDEQL
MDMA	ng/g	AMPS-MDMQL
Methamphetamine	ng/g	AMPS-METHQL

52362UC Cannabinoids Confirmation (Qualitative), Umbilical Cord Tissue- Current Version
Analyte	Units	Analyte Mapping Code
Delta-9 Carboxy THC	ng/g	THC1-9CAQL

52363UC Cocaine Metabolite Confirmation (Qualitative), Umbilical Cord Tissue- Current Version
Analyte	Units	Analyte Mapping Code
Benzoylecgonine	ng/g	TOF3-ECGQL

52391UC Opiates - Free (Unconjugated) Confirmation (Qualitative), Umbilical Cord Tissue- Current Version
Analyte	Units	Analyte Mapping Code
6-Monoacetylmorphine - Free	ng/g	TOF5-MAMQL
Codeine - Free	ng/g	TOF5-CODQL
Hydrocodone - Free	ng/g	TOF5-HYDQL
Hydromorphone - Free	ng/g	TOF5-HMFQL
Morphine - Free	ng/g	TOF5-MORQL

52357UC Phencyclidine Confirmation (Qualitative), Umbilical Cord Tissue- Current Version
Analyte	Units	Analyte Mapping Code
Phencyclidine	ng/g	PHENCYCLQL

LOINC^® Information

9351UC Basic Drug Screen, Umbilical Cord Tissue - Current Version
Analyte	Units	Analyte Mapping Code	LOINC®
6-Monoacetylmorphine - Free	ng/g	TOF5-MAMF	97210-9
Amphetamine	ng/g	AMPS-AMPH	97220-8
Benzoylecgonine	ng/g	TOF3-ECGON	97222-4
Codeine - Free	ng/g	TOF5-CODEI	97236-4
Delta-9 Carboxy THC	ng/g	THC1-9CARB	97584-7
Hydrocodone - Free	ng/g	TOF5-HYDROC	97254-7
Hydromorphone - Free	ng/g	TOF5-HMF	97256-2
MDA	ng/g	AMPS-MDA1	97262-0
MDEA	ng/g	AMPS-MDEA	97264-6
MDMA	ng/g	AMPS-MDMA	97266-1
Methamphetamine	ng/g	AMPS-METHA	97274-5
Morphine - Free	ng/g	TOF5-MORPH	97280-2
Phencyclidine	ng/g	PHENCYCL	97298-4

52345UC Amphetamines Confirmation (Qualitative), Umbilical Cord Tissue - Current Version
Analyte	LOINC®
Amphetamine	97221-6
MDA	97263-8
MDEA	97265-3
MDMA	97267-9
Methamphetamine	97275-2

52362UC Cannabinoids Confirmation (Qualitative), Umbilical Cord Tissue - Current Version
Analyte	LOINC®
Delta-9 Carboxy THC	97585-4

52363UC Cocaine Metabolite Confirmation (Qualitative), Umbilical Cord Tissue - Current Version
Analyte	LOINC®
Benzoylecgonine	97223-2

52391UC Opiates - Free (Unconjugated) Confirmation (Qualitative), Umbilical Cord Tissue - Current Version
Analyte	LOINC®
6-Monoacetylmorphine - Free	97211-7
Codeine - Free	97237-2
Hydrocodone - Free	97255-4
Hydromorphone - Free	97257-0
Morphine - Free	97281-0

52357UC Phencyclidine Confirmation (Qualitative), Umbilical Cord Tissue - Current Version
Analyte	LOINC®
Phencyclidine	97299-2

Some LOINC^® codes may not have been assigned or are not available.

This material contains content from LOINC (http://loinc.org). LOINC is copyright ^® 1995-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC^® is a registered United States trademark of Regenstrief Institute, Inc.

The CPT Codes provided in this document are based on AMA Guidelines and are for informational purposes only. NMS Labs Does not assume responsibility for billing errors due to Reliance on the CPT Codes listed in this document.

*The information contained in this document represents database configurations, as they will appear on the effective date listed above.